<b>An enzymatic microassay method for deoxyglucose and deoxyglucose </b><b>6-phosphate </b>

Deoxyglucose Method For Measurement Of Local Cerebral Glucose Utilisation

Synthesis, Radiolabeling and Biological Evaluation of 99mTc-labeled Deoxyglucose Derivatives for Molecular Imaging

Two deoxyglucose (DG) derivatives, (α,β)-2-deoxy-2-amino(ethylcarbamate)-D-glucose (ECB-DG) and (α,β)-2-deoxy-2-amino(1,2-dihydroxypropyl)-D-glucose (DHP-DG), were synthesized and radiolabeled successfully with [99mTc(H2O)3(CO)3]+ complex. [99mTc]-ECB-DG and [99mTc]-DHP-DG complexes were prepared (96% and 93% radiochemical purities respectively) by using 46 mCi of Na99mTcO4 in 1 mL saline. Radi...

Effect of 2-deoxyglucose on Schizosaccharomyces pombe.

Megnet, Roland (Institut für Allgemeine Mikrobiologie der Universität, Bern, Switzerland). Effect of 2-deoxyglucose on Schizosaccharomyces pombe. J. Bacteriol. 90:1032-1035. 1965.-Cultivation of Schizosaccaromyces pombe in a medium containing 2-deoxyglucose (100 mug/ml) results in the death of the cells after an initial period of apparently normal growth. At higher deoxyglucose concentration (4...

Synthesis, Radiolabeling and Biological Evaluation of 99mTc-labeled Deoxyglucose Derivatives for Molecular Imaging

Two deoxyglucose (DG) derivatives, (α,β)-2-deoxy-2-amino(ethylcarbamate)-D-glucose (ECB-DG) and (α,β)-2-deoxy-2-amino(1,2-dihydroxypropyl)-D-glucose (DHP-DG), were synthesized and radiolabeled successfully with [99mTc(H2O)3(CO)3]+ complex. [99mTc]-ECB-DG and [99mTc]-DHP-DG complexes were prepared (96% and 93% radiochemical purities respectively) by using 46 mCi of Na99mTcO4 in 1 mL saline. Radi...

Metabolism of Ascites Tumor Cells. Iv. Enzymatic Reactions Involved in Adenosinetriphosphate Degradation Induced by 2-deoxyglucose.

The changes in cellular nucleotides accompanying the phosphorylation of 2-deoxyglucose by respiring Krebs ascites tumor cells have been studied. The degradation of ATP by dephosphorylation and deamination to form ADP, AMP, IMP, and inosine in 2-deoxyglucose-treated cells was followed chromatographically and electrophoretically. A rise in cellular AMP concentration, a rise and subsequent fall in...